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SMN-primed ribosomes modulate the translation of transcripts related to Spinal Muscular Atrophy

The contribution of ribosome heterogeneity and ribosome-associated proteins to the molecular control of proteomes in health and disease remains enigmatic. We demonstrate that Survival Motor Neuron (SMN) protein, loss of which causes the neuromuscular disease spinal muscular atrophy (SMA), binds to r...

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Detalles Bibliográficos
Autores principales:	Lauria, Fabio, Bernabò, Paola, Tebaldi, Toma, Groen, Ewout Joan Nicolaas, Perenthaler, Elena, Maniscalco, Federica, Rossi, Annalisa, Donzel, Deborah, Clamer, Massimiliano, Marchioretto, Marta, Omersa, Neža, Orri, Julia, Serra, Mauro Dalla, Anderluh, Gregor, Quattrone, Alessandro, Inga, Alberto, Gillingwater, Thomas Henry, Viero, Gabriella
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7610479/ https://www.ncbi.nlm.nih.gov/pubmed/32958857 http://dx.doi.org/10.1038/s41556-020-00577-7

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