Cargando…
Single-molecule visualisation of DNA G-quadruplex formation in live cells
Substantial evidence now exists to support that formation of DNA G-quadruplexes (G4s) can alter gene-expression. However, approaches that allow to probe G4s in living cells without perturbing their folding dynamics are required to understand their biological roles in greater detail. Herein, we repor...
Autores principales: | Di Antonio, Marco, Ponjavic, Aleks, Radzevičius, Antanas, Ranasinghe, Rohan T., Catalano, Marco, Zhang, Xiaoyun, Shen, Jiazhen, Needham, Lisa-Maria, Lee, Steven F., Klenerman, David, Balasubramanian, Shankar |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7610488/ https://www.ncbi.nlm.nih.gov/pubmed/32690897 http://dx.doi.org/10.1038/s41557-020-0506-4 |
Ejemplares similares
-
Promoter G-quadruplex folding precedes transcription and is controlled by chromatin
por: Shen, Jiazhen, et al.
Publicado: (2021) -
Single molecule conformational analysis of DNA G-quadruplexes
por: Shirude, Pravin S., et al.
Publicado: (2008) -
Chemical profiling of DNA G-quadruplex-interacting proteins in live cells
por: Zhang, Xiaoyun, et al.
Publicado: (2021) -
Machine learning model for sequence-driven DNA G-quadruplex formation
por: Sahakyan, Aleksandr B., et al.
Publicado: (2017) -
Visualising G-quadruplex DNA dynamics in live cells by fluorescence lifetime imaging microscopy
por: Summers, Peter A., et al.
Publicado: (2021)