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Regulation of single-cell genome organization into TADs and chromatin nanodomains
The genome folds into a hierarchy of three-dimensional (3D) structures within the nucleus. At the sub-megabase scale, chromosomes form topologically associating domains (TADs)(1–4). However, how TADs fold in single cells remains elusive. Here, we revealed TAD features inaccessible to cell-population...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7610512/ https://www.ncbi.nlm.nih.gov/pubmed/33077913 http://dx.doi.org/10.1038/s41588-020-00716-8 |