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Determining protein structures using deep mutagenesis

Determining the three-dimensional (3D) structures of macromolecules is a major goal of biological research because of the close relationship between structure and function but thousands of protein domains still have unknown structures. Structure determination usually relies on physical techniques in...

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Detalles Bibliográficos
Autores principales: Schmiedel, Jörn M., Lehner, Ben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7610650/
https://www.ncbi.nlm.nih.gov/pubmed/31209395
http://dx.doi.org/10.1038/s41588-019-0431-x