Cargando…
Determining protein structures using deep mutagenesis
Determining the three-dimensional (3D) structures of macromolecules is a major goal of biological research because of the close relationship between structure and function but thousands of protein domains still have unknown structures. Structure determination usually relies on physical techniques in...
Autores principales: | Schmiedel, Jörn M., Lehner, Ben |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7610650/ https://www.ncbi.nlm.nih.gov/pubmed/31209395 http://dx.doi.org/10.1038/s41588-019-0431-x |
Ejemplares similares
-
DiMSum: an error model and pipeline for analyzing deep mutational scanning data and diagnosing common experimental pathologies
por: Faure, Andre J., et al.
Publicado: (2020) -
Empirical mean-noise fitness landscapes reveal the fitness impact of gene expression noise
por: Schmiedel, Jörn M., et al.
Publicado: (2019) -
SUNi mutagenesis: Scalable and uniform nicking for efficient generation of variant libraries
por: Mighell, Taylor L., et al.
Publicado: (2023) -
The mutational landscape of a prion-like domain
por: Bolognesi, Benedetta, et al.
Publicado: (2019) -
Determination of absorption dose in chemical mutagenesis in plants
por: Ke, Changjiao, et al.
Publicado: (2019)