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Investigating higher order interactions in single cell data with scHOT
Single-cell genomics has transformed our ability to examine cell fate choice. Examining cells along a computationally ordered “pseudotime” offers the potential to unpick subtle changes in variability and covariation among key genes. We describe a novel approach, scHOT – single cell Higher Order Test...
Autores principales: | Ghazanfar, Shila, Lin, Yingxin, Su, Xianbin, Lin, David Ming, Patrick, Ellis, Han, Ze Guang, Marioni, John C., Yang, Jean Yee Hwa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7610653/ https://www.ncbi.nlm.nih.gov/pubmed/32661426 http://dx.doi.org/10.1038/s41592-020-0885-x |
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