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Exaggerated IL-17A activity in human in vivo recall responses discriminates active tuberculosis from latent infection and cured disease

Host immune responses at the site of Mycobacterium tuberculosis (Mtb) infection can mediate pathogenesis of tuberculosis (TB) and onward transmission of infection. We hypothesized that pathological immune responses would be enriched at the site of host-pathogen interactions modelled by a standardize...

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Detalles Bibliográficos
Autores principales:	Pollara, Gabriele, Turner, Carolin T, Rosenheim, Joshua, Chandran, Aneesh, Bell, Lucy CK, Khan, Ayesha, Patel, Amit, Peralta, Luis Felipe, Folino, Anna, Akarca, Ayse, Venturini, Cristina, Baker, Tina, Ecker, Simone, Ricciardolo, Fabio LM, Marafioti, Teresa, Ugarte-Gil, Cesar, Moore, David AJ, Chain, Benjamin M, Tomlinson, Gillian S, Noursadeghi, Mahdad
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7610803/ https://www.ncbi.nlm.nih.gov/pubmed/33952677 http://dx.doi.org/10.1126/scitranslmed.abg7673

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