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Characterizing Hepatitis C Virus–Specific CD4(+) T Cells Following Viral‐Vectored Vaccination, Directly Acting Antivirals, and Spontaneous Viral Cure

BACKGROUND AND AIMS: Induction of functional helper CD4(+) T cells is the hallmark of a protective immune response against hepatitis C virus (HCV), associated with spontaneous viral clearance. Heterologous prime/boost viral vectored vaccination has demonstrated induction of broad and polyfunctional...

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Detalles Bibliográficos
Autores principales: Hartnell, Felicity, Esposito, Ilaria, Swadling, Leo, Brown, Anthony, Phetsouphanh, Chansavath, de Lara, Catherine, Gentile, Chiara, Turner, Bethany, Dorrell, Lucy, Capone, Stefania, Folgori, Antonella, Barnes, Eleanor, Klenerman, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7610807/
https://www.ncbi.nlm.nih.gov/pubmed/32012325
http://dx.doi.org/10.1002/hep.31160

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