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Combined single-cell and spatial transcriptomics reveals the molecular, cellular and spatial bone marrow niche organization
The bone marrow (BM) constitutes the primary site for life-long blood production and skeletal regeneration. However, its cellular composition and the spatial organization into distinct ‘niches’ remains controversial. Here, we combine single-cell and spatially resolved transcriptomics to systematical...
Autores principales: | Baccin, Chiara, Al-Sabah, Jude, Velten, Lars, Helbling, Patrick M., Grünschläger, Florian, Hernández-Malmierca, Pablo, Nombela-Arrieta, César, Steinmetz, Lars M., Trumpp, Andreas, Haas, Simon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7610809/ https://www.ncbi.nlm.nih.gov/pubmed/31871321 http://dx.doi.org/10.1038/s41556-019-0439-6 |
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