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The Roles of Type 2 Cytotoxic T Cells in Inflammation, Tissue Remodeling, and Prostaglandin (PG) D(2) Production Are Attenuated by PGD(2) Receptor 2 Antagonism

Human type 2 cytotoxic T (Tc2) cells are enriched in severe eosinophilic asthma and can contribute to airway eosinophilia. PGD(2) and its receptor PGD(2) receptor 2 (DP2) play important roles in Tc2 cell activation, including migration, cytokine production, and survival. In this study, we revealed n...

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Detalles Bibliográficos
Autores principales:	Chen, Wentao, Luo, Jian, Ye, Yuan, Hoyle, Ryan, Liu, Wei, Borst, Rowie, Kazani, Shamsah, Shikatani, Eric A., Erpenbeck, Veit J., Pavord, Ian D., Klenerman, Paul, Sandham, David A., Xue, Luzheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AAI 2021
Materias:	Mucosal Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7610864/ https://www.ncbi.nlm.nih.gov/pubmed/34011519 http://dx.doi.org/10.4049/jimmunol.2001245

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