Prokaryotic viperins produce diverse antiviral molecules

Viperin is an interferon-induced cellular protein conserved in animals. It was shown to inhibit the replication of multiple viruses by producing a ribonucleotide called 3’-deoxy-3’4’-didehydro-CTP (ddhCTP), which acts as a chain terminator for the viral RNA polymerase. Here we show that the eukaryot...

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Detalles Bibliográficos
Autores principales: Bernheim, Aude, Millman, Adi, Ofir, Gal, Meitav, Gilad, Avraham, Carmel, Shomar, Helena, Rosenberg, Masha M., Tal, Nir, Melamed, Sarah, Amitai, Gil, Sorek, Rotem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7610908/
https://www.ncbi.nlm.nih.gov/pubmed/32937646
http://dx.doi.org/10.1038/s41586-020-2762-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7610908/
https://www.ncbi.nlm.nih.gov/pubmed/32937646
http://dx.doi.org/10.1038/s41586-020-2762-2

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