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Functional human IgA targets a conserved site on malaria sporozoites

Immunoglobulin (Ig)A antibodies play a critical role in protection against mucosal pathogens. However, the role of serum IgA in immunity to non-mucosal pathogens, such as Plasmodium falciparum, is poorly characterized, despite being the second most abundant isotype in blood after IgG. Here, we inves...

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Detalles Bibliográficos
Autores principales:	Tan, Joshua, Cho, Hyeseon, Pholcharee, Tossapol, Pereira, Lais S., Doumbo, Safiatou, Doumtabe, Didier, Flynn, Barbara J., Schön, Arne, Kanatani, Sachie, Aylor, Samantha O., Oyen, David, Vistein, Rachel, Wang, Lawrence, Dillon, Marlon, Skinner, Jeff, Peterson, Mary, Li, Shanping, Idris, Azza H., Molina-Cruz, Alvaro, Zhao, Ming, Olano, Lisa Renee, Lee, Patricia J., Roth, Alison, Sinnis, Photini, Barillas-Mury, Carolina, Kayentao, Kassoum, Ongoiba, Aissata, Francica, Joseph R., Traore, Boubacar, Wilson, Ian A., Seder, Robert A., Crompton, Peter D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7611206/ https://www.ncbi.nlm.nih.gov/pubmed/34162751 http://dx.doi.org/10.1126/scitranslmed.abg2344

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