Cargando…
Malaria exposure drives both cognate and bystander human B cells to adopt an atypical phenotype
Atypical memory B cells (aMBCs) are found in elevated numbers in individuals exposed to malaria. A key question is whether malaria induces aMBCs as a result of exposure to Ag, or non-Ag-specific mechanisms. We identified Plasmodium and bystander tetanus toxoid (TT) specific B cells in individuals fr...
Autores principales: | Aye, Racheal, Sutton, Henry J., Nduati, Eunice W., Kai, Oscar, Mwacharo, Jedida, Musyoki, Jennifer, Otieno, Edward, Wambua, Juliana, Bejon, Philip, Cockburn, Ian A., Ndungu, Francis M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7611263/ https://www.ncbi.nlm.nih.gov/pubmed/32222961 http://dx.doi.org/10.1002/eji.201948473 |
Ejemplares similares
-
A seven-year study on the effect of the pre-erythrocytic malaria vaccine candidate RTS,S/AS01
(E) on blood stage immunity in young Kenyan children
por: Ndungu, Francis M., et al.
Publicado: (2019) -
Seven-year kinetics of RTS, S/AS01-induced anti-CSP antibodies in young Kenyan children
por: Mugo, Robert M., et al.
Publicado: (2021) -
Atypical B cells are part of an alternative lineage of B cells that participates in responses to vaccination and infection in humans
por: Sutton, Henry J., et al.
Publicado: (2021) -
10-year longitudinal study of malaria in children: Insights into acquisition and maintenance of naturally acquired immunity
por: Addy, John W.G., et al.
Publicado: (2022) -
Individual-level variations in malaria susceptibility and acquisition of clinical protection
por: Valletta, John Joseph, et al.
Publicado: (2022)