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Cell fate coordinates mechano-osmotic forces in intestinal crypt formation
Intestinal organoids derived from single cells undergo complex crypt-villus patterning and morphogenesis. However, the nature and coordination of the underlying forces remains poorly characterized. Through light-sheet microscopy and large-scale imaging quantification, we demonstrate that crypt forma...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7611267/ https://www.ncbi.nlm.nih.gov/pubmed/34155381 http://dx.doi.org/10.1038/s41556-021-00700-2 |