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Single-molecule imaging of LexA degradation in Escherichia coli elucidates regulatory mechanisms and heterogeneity of the SOS response

The bacterial SOS response stands as a paradigm of gene networks controlled by a master transcriptional regulator. Self-cleavage of the SOS repressor, LexA, induces a wide range of cell functions that are critical for survival and adaptation when bacteria experience stress conditions(1), including D...

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Detalles Bibliográficos
Autores principales: Jones, Emma C., Uphoff, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7611437/
https://www.ncbi.nlm.nih.gov/pubmed/34183814
http://dx.doi.org/10.1038/s41564-021-00930-y