Switching-on Prodrugs Using Radiotherapy

Chemotherapy is a powerful tool in the armoury against cancer, however it is fraught with problems due to global systemic toxicity. Here we report the proof-of-concept of a chemistry-based strategy, whereby gamma/X-ray irradiation mediates the activation of a cancer prodrug thereby enabling simultan...

Descripción completa

Detalles Bibliográficos
Autores principales: Geng, Jin, Zhang, Yichuan, Gao, Quan, Neumann, Kevin, Dong, Hua, Porter, Hamish, Potter, Mark, Ren, Hua, Argyle, David, Bradley, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7611443/
https://www.ncbi.nlm.nih.gov/pubmed/34112990
http://dx.doi.org/10.1038/s41557-021-00711-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7611443/
https://www.ncbi.nlm.nih.gov/pubmed/34112990
http://dx.doi.org/10.1038/s41557-021-00711-4

Ejemplares similares