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Switching-on Prodrugs Using Radiotherapy
Chemotherapy is a powerful tool in the armoury against cancer, however it is fraught with problems due to global systemic toxicity. Here we report the proof-of-concept of a chemistry-based strategy, whereby gamma/X-ray irradiation mediates the activation of a cancer prodrug thereby enabling simultan...
Autores principales: | Geng, Jin, Zhang, Yichuan, Gao, Quan, Neumann, Kevin, Dong, Hua, Porter, Hamish, Potter, Mark, Ren, Hua, Argyle, David, Bradley, Mark |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7611443/ https://www.ncbi.nlm.nih.gov/pubmed/34112990 http://dx.doi.org/10.1038/s41557-021-00711-4 |
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