Structure of the shutdown state of myosin-2

Myosin-2 is essential for processes as diverse as cell division and muscle contraction. Dephosphorylation of its regulatory light chain (RLC) promotes an inactive, ‘shutdown’ state with the filament-forming tail folded onto the two heads(1), preventing filament formation and inactivating the motors(...

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Detalles Bibliográficos
Autores principales: Scarff, Charlotte A, Carrington, Glenn, Casas-Mao, David, Chalovich, Joseph M, Knight, Peter J, Ranson, Neil A, Peckham, Michelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7611489/
https://www.ncbi.nlm.nih.gov/pubmed/33268888
http://dx.doi.org/10.1038/s41586-020-2990-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7611489/
https://www.ncbi.nlm.nih.gov/pubmed/33268888
http://dx.doi.org/10.1038/s41586-020-2990-5

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