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Structure of the shutdown state of myosin-2
Myosin-2 is essential for processes as diverse as cell division and muscle contraction. Dephosphorylation of its regulatory light chain (RLC) promotes an inactive, ‘shutdown’ state with the filament-forming tail folded onto the two heads(1), preventing filament formation and inactivating the motors(...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7611489/ https://www.ncbi.nlm.nih.gov/pubmed/33268888 http://dx.doi.org/10.1038/s41586-020-2990-5 |