Cell competition acts as a purifying selection to eliminate cells with mitochondrial defects during early mouse development

Cell competition is emerging as a quality control mechanism that eliminates unfit cells in a wide range of settings from development to the adult. However, the nature of the cells normally eliminated by cell competition and what triggers their elimination remains poorly understood. In mice, 35% of e...

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Detalles Bibliográficos
Autores principales: Lima, Ana, Lubatti, Gabriele, Burgstaller, Jörg, Hu, Di, Green, Alistair P., Di Gregorio, Aida, Zawadzki, Tamzin, Pernaute, Barbara, Mahammadov, Elmir, Perez-Montero, Salvador, Dore, Marian, Sanchez, Juan Miguel, Bowling, Sarah, Sancho, Margarida, Kolbe, Thomas, Karimi, Mohammad M., Carling, David, Jones, Nick, Srinivas, Shankar, Scialdone, Antonio, Rodriguez, Tristan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7611553/
https://www.ncbi.nlm.nih.gov/pubmed/34253906
http://dx.doi.org/10.1038/s42255-021-00422-7

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