Leptin brain entry via a tanycytic LepR:EGFR shuttle controls lipid metabolism and pancreas function

Metabolic health depends on the brain’s ability to control food intake and nutrient use versus storage, processes that require peripheral signals such as the adipocyte-derived hormone, leptin, to cross brain barriers and mobilize regulatory circuits. We have previously shown that hypothalamic tanycy...

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Detalles Bibliográficos
Autores principales: Duquenne, Manon, Folgueira, Cintia, Bourouh, Cyril, Millet, Marion, Silva, Anisia, Clasadonte, Jérôme, Imbernon, Monica, Fernandois, Daniela, Martinez-Corral, Ines, Kusumakshi, Soumya, Caron, Emilie, Rasika, S., Deliglia, Eleonora, Jouy, Nathalie, Oishi, Asturo, Mazzone, Massimiliano, Trinquet, Eric, Tavernier, Jan, Kim, Young-Bum, Ory, Stéphane, Jockers, Ralf, Schwaninger, Markus, Boehm, Ulrich, Nogueiras, Ruben, Annicotte, Jean-Sébastien, Gasman, Stéphane, Dam, Julie, Prévot, Vincent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7611554/
https://www.ncbi.nlm.nih.gov/pubmed/34341568
http://dx.doi.org/10.1038/s42255-021-00432-5

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