ILC1 drive intestinal epithelial and matrix remodelling

Organoids can shed light on the dynamic interplay between complex tissues and rare cell types within a controlled microenvironment. Here, we developed gut organoid co-cultures with type-1 innate lymphoid cells (ILC1) to dissect the impact of their accumulation in inflamed intestines. We demonstrate...

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Detalles Bibliográficos
Autores principales: Jowett, Geraldine M., Norman, Michael D. A., Yu, Tracy T. L., Arévalo, Patricia Rosell, Hoogland, Dominique, Lust, Suzette T., Read, Emily, Hamrud, Eva, Walters, Nick J., Niazi, Umar, Chung, Matthew Wai Heng, Marciano, Daniele, Omer, Omer Serhan, Zabinski, Tomasz, Danovi, Davide, Lord, Graham M., Hilborn, Jöns, Evans, Nicholas D., Dreiss, Cécile A., Bozec, Laurent, Oommen, Oommen P., Lorenz, Christian D., da Silva, Ricardo M.P., Neves, Joana F., Gentleman, Eileen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7611574/
https://www.ncbi.nlm.nih.gov/pubmed/32895507
http://dx.doi.org/10.1038/s41563-020-0783-8

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