Decoding myofibroblast origins in human kidney fibrosis

Kidney fibrosis is the hallmark of chronic kidney disease progression, however, currently no antifibrotic therapies exist. This is largely because the origin, functional heterogeneity and regulation of scar-forming cells during human kidney fibrosis remains poorly understood. Here, using single cell...

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Detalles Bibliográficos
Autores principales: Kuppe, Christoph, Ibrahim, Mahmoud M, Kranz, Jennifer, Zhang, Xiaoting, Ziegler, Susanne, Perales-Patón, Javier, Jansen, Jitske, Reimer, Katharina C., Smith, James R., Dobie, Ross, Wilson-Kanamari, John R., Halder, Maurice, Xu, Yaoxian, Kabgani, Nazanin, Kaesler, Nadine, Klaus, Martin, Gernhold, Lukas, Puelles, Victor G., Huber, Tobias B., Boor, Peter, Menzel, Sylvia, Hoogenboezem, Remco M., Bindels, Eric M.J., Steffens, Joachim, Floege, Jürgen, Schneider, Rebekka K, Saez-Rodriguez, Julio, Henderson, Neil C, Kramann, Rafael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7611626/
https://www.ncbi.nlm.nih.gov/pubmed/33176333
http://dx.doi.org/10.1038/s41586-020-2941-1

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