Effector differentiation downstream of lineage commitment in ILC1 is driven by Hobit across tissues

Innate lymphoid cells (ILCs) participate in tissue homeostasis, inflammation and early immunity against infection. It is unclear how ILCs acquire effector function, and whether these mechanisms differ between organs. Through multiplexed single-cell mRNA-sequencing we identified cKit(+)CD127(hi)TCF-1...

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Detalles Bibliográficos
Autores principales: Friedrich, Christin, Taggenbrock, Renske L. R. E., Doucet-Ladevèze, Rémi, Golda, Gosia, Moenius, Rebekka, Arampatzi, Panagiota, Kragten, Natasja A. M., Kreymborg, Katharina, de Agüero, Mercedes Gomez, Kastenmueller, Wolfgang, Saliba, Antoine-Emmanuel, Grün, Dominic, van Gisbergen, Klaas P. J. M., Gasteiger, Georg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7611762/
https://www.ncbi.nlm.nih.gov/pubmed/34462601
http://dx.doi.org/10.1038/s41590-021-01013-0

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