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Mutation Signatures of Pediatric Acute Myeloid Leukemia and Normal Blood Progenitors Associated with Differential Patient Outcomes

Acquisition of oncogenic mutations with age is believed to be rate limiting for carcinogenesis. However, the incidence of leukemia in children is higher than in young adults. Here we compare somatic mutations across pediatric acute myeloid leukemia (pAML) patient-matched leukemic blasts and hematopo...

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Detalles Bibliográficos
Autores principales:	Brandsma, Arianne M., Bertrums, Eline J.M., van Roosmalen, Markus J., Hofman, Damon A., Oka, Rurika, Verheul, Mark, Manders, Freek, Ubels, Joske, Belderbos, Mirjam E., van Boxtel, Ruben
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for Cancer Research 2021
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7611805/ https://www.ncbi.nlm.nih.gov/pubmed/34642666 http://dx.doi.org/10.1158/2643-3230.BCD-21-0010

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