Loss of function mutations in the melanocortin 4 receptor in a UK birth cohort

Mutations in the melanocortin 4 receptor gene (MC4R) are associated with obesity but little is known about the prevalence and impact of such mutations throughout human growth and development. We examined the MC4R coding sequence in 5724 participants from the Avon Longitudinal Study of Parents and Ch...

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Detalles Bibliográficos
Autores principales: Wade, Kaitlin H, Lam, Brian YH, Melvin, Audrey, Pan, Warren, Corbin, Laura J, Hughes, David A, Rainbow, Kara, Chen, Jian-Hua, Duckett, Katie, Liu, Xiaoming, Mokrosiński, Jacek, Mörseburg, Alexander, Neaves, Sam, Williamson, Alice, Zhang, Chen, Farooqi, I. Sadaf, Yeo, Giles SH, Timpson, Nicholas J, O’Rahilly, Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7611835/
https://www.ncbi.nlm.nih.gov/pubmed/34045736
http://dx.doi.org/10.1038/s41591-021-01349-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7611835/
https://www.ncbi.nlm.nih.gov/pubmed/34045736
http://dx.doi.org/10.1038/s41591-021-01349-y

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