Cargando…

A Chemically Defined Hydrogel for Human Liver Organoid Culture

End-stage liver diseases are an increasing health burden, and liver transplantations are currently the only curative treatment option. Due to a lack of donor livers, alternative treatments are urgently needed. Human liver organoids are very promising for regenerative medicine; however, organoids are...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ye, Shicheng, Boeter, Jochem W.B., Mihajlovic, Marko, van Steenbeek, Frank G., van Wolferen, Monique E., Oosterhoff, Loes A., Marsee, Ary, Caiazzo, Massimiliano, van der Laan, Luc J.W., Penning, Louis C., Vermonden, Tina, Spee, Bart, Schneeberger, Kerstin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7611838/ https://www.ncbi.nlm.nih.gov/pubmed/34658689 http://dx.doi.org/10.1002/adfm.202000893

Ejemplares similares

Hydrogels for Liver Tissue Engineering
por: Ye, Shicheng, et al.
Publicado: (2019)

Identification of potential drugs for treatment of hepatic lipidosis in cats using an in vitro feline liver organoid system
por: Haaker, Maya W., et al.
Publicado: (2019)

High level of polarized engraftment of porcine intrahepatic cholangiocyte organoids in decellularized liver scaffolds
por: Krüger, Melanie, et al.
Publicado: (2022)

Intestinal Organoids—Current and Future Applications
por: Meneses, Andre M. C., et al.
Publicado: (2016)

Large‐Scale Production of LGR5‐Positive Bipotential Human Liver Stem Cells
por: Schneeberger, Kerstin, et al.
Publicado: (2020)

Long-Term Adult Feline Liver Organoid Cultures for Disease Modeling of Hepatic Steatosis
por: Kruitwagen, Hedwig S., et al.
Publicado: (2017)

Characterization and Comparison of Canine Multipotent Stromal Cells Derived from Liver and Bone Marrow
por: Malagola, Ermanno, et al.
Publicado: (2016)

Long-Term Survival of Transplanted Autologous Canine Liver Organoids in a COMMD1-Deficient Dog Model of Metabolic Liver Disease
por: Kruitwagen, Hedwig S., et al.
Publicado: (2020)

Hepatocyte‐like cells generated by direct reprogramming from murine somatic cells can repopulate decellularized livers
por: Chen, Chen, et al.
Publicado: (2018)

Reduced FXR Target Gene Expression in Copper-Laden Livers of COMMD1-Deficient Dogs
por: Wu, Xiaoyan, et al.
Publicado: (2019)

Disease Modeling and Gene Therapy of Copper Storage Disease in Canine Hepatic Organoids
por: Nantasanti, Sathidpak, et al.
Publicado: (2015)

Drug Metabolism of Hepatocyte-like Organoids and Their Applicability in In Vitro Toxicity Testing
por: Bouwmeester, Manon C., et al.
Publicado: (2023)

Characterization of Endothelial and Smooth Muscle Cells From Different Canine Vessels
por: Oosterhoff, Loes A., et al.
Publicado: (2019)

Association of circulating microRNA‐122 and microRNA‐29a with stage of fibrosis and progression of chronic hepatitis in Labrador Retrievers
por: Sakai, Manabu, et al.
Publicado: (2018)

A human kidney and liver organoid‐based multi‐organ‐on‐a‐chip model to study the therapeutic effects and biodistribution of mesenchymal stromal cell‐derived extracellular vesicles
por: Nguyen, Vivian V. T., et al.
Publicado: (2022)

Toward Transplantation of Liver Organoids: From Biology and Ethics to Cost-effective Therapy
por: ten Dam, Marjolein J.M., et al.
Publicado: (2023)

Bioengineering Liver Transplantation
por: Verstegen, Monique M.A., et al.
Publicado: (2019)

Bile Duct Repair in Human Liver Grafts: Effective Cholangiocyte Organoid Engraftment and Plasticity
por: van der Laan, Luc J.W., et al.
Publicado: (2021)

Enhanced Wnt/β-catenin and Notch signalling in the activated canine hepatic progenitor cell niche
por: Schotanus, Baukje A, et al.
Publicado: (2014)

Protocol for inducing branching morphogenesis in human cholangiocyte and cholangiocarcinoma organoids
por: Ober, Kimberley, et al.
Publicado: (2023)

Cellular characteristics of keratin 19-positive canine hepatocellular tumours explain its aggressive behaviour
por: van Sprundel, Renee G, et al.
Publicado: (2017)

Locational memory of macrovessel vascular cells is transcriptionally imprinted
por: Spanjersberg, Talitha C. F., et al.
Publicado: (2023)

Creating a Functional Biomimetic Cartilage Implant Using Hydrogels Based on Methacrylated Chondroitin Sulfate and Hyaluronic Acid
por: Schuiringa, Gerke H., et al.
Publicado: (2022)

Brain Organoids: Filling the Need for a Human Model of Neurological Disorder
por: Jalink, Philip, et al.
Publicado: (2021)

Liver Organoids: Updates on Disease Modeling and Biomedical Applications
por: Caiazza, Carmen, et al.
Publicado: (2021)

Generation of Differentiating and Long-Living Intestinal Organoids Reflecting the Cellular Diversity of Canine Intestine
por: Kramer, Nina, et al.
Publicado: (2020)

The potential and limitations of intrahepatic cholangiocyte organoids to study inborn errors of metabolism
por: Lehmann, Vivian, et al.
Publicado: (2021)

Modelling metastatic colonization of cholangiocarcinoma organoids in decellularized lung and lymph nodes
por: van Tienderen, Gilles S., et al.
Publicado: (2023)

Design by Nature: Emerging Applications of Native Liver Extracellular Matrix for Cholangiocyte Organoid-Based Regenerative Medicine
por: Willemse, Jorke, et al.
Publicado: (2022)

Human Cholangiocytes Form a Polarized and Functional Bile Duct on Hollow Fiber Membranes
por: Wang, Zhenguo, et al.
Publicado: (2022)

Recreating Tumour Complexity in a Dish: Organoid Models to Study Liver Cancer Cells and their Extracellular Environment
por: van Tienderen, Gilles S., et al.
Publicado: (2019)

Local changes in microtubule network mobility instruct neuronal polarization and axon specification
por: Burute, Mithila, et al.
Publicado: (2022)

Emerging organoid-immune co-culture models for cancer research: from oncoimmunology to personalized immunotherapies
por: Magré, Luc, et al.
Publicado: (2023)

Protocol for generating airway organoids from 2D air liquid interface-differentiated nasal epithelia for use in a functional CFTR assay
por: Rodenburg, Lisa W., et al.
Publicado: (2023)

Gene Expression Profiling of Histiocytic Sarcomas in a Canine Model: The Predisposed Flatcoated Retriever Dog
por: Boerkamp, Kim M., et al.
Publicado: (2013)

Recapitulating Cholangiopathy-Associated Necroptotic Cell Death In Vitro Using Human Cholangiocyte Organoids
por: Shi, Shaojun, et al.
Publicado: (2021)

Scalable Production of Size-Controlled Cholangiocyte and Cholangiocarcinoma Organoids within Liver Extracellular Matrix-Containing Microcapsules
por: van Tienderen, Gilles S., et al.
Publicado: (2022)

Aberrant hepatic lipid storage and metabolism in canine portosystemic shunts
por: Van den Bossche, Lindsay, et al.
Publicado: (2017)

Prediction of outcome after ligation or thin film banding of extrahepatic shunts, based on plasma albumin concentration and hematologic expression of 8 target genes in 85 dogs
por: van Blokland‐Post, Krista, et al.
Publicado: (2023)

Kinome profiling of cholangiocarcinoma organoids reveals potential druggable targets that hold promise for treatment stratification
por: Lieshout, Ruby, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_s4a0v4sjsl5taqam5mhi32stro