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Reversible amyloids of pyruvate kinase couple cell metabolism and stress granule disassembly
Cells respond to stress by blocking translation, rewiring metabolism, and forming transient mRNP assemblies called stress granules (SGs). After stress release, re-establishing homeostasis and disassemblying SGs requires ATP-consuming processes. However, the molecular mechanisms whereby cells restore...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7611853/ https://www.ncbi.nlm.nih.gov/pubmed/34616026 http://dx.doi.org/10.1038/s41556-021-00760-4 |