Reversible amyloids of pyruvate kinase couple cell metabolism and stress granule disassembly

Cells respond to stress by blocking translation, rewiring metabolism, and forming transient mRNP assemblies called stress granules (SGs). After stress release, re-establishing homeostasis and disassemblying SGs requires ATP-consuming processes. However, the molecular mechanisms whereby cells restore...

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Detalles Bibliográficos
Autores principales: Cereghetti, Gea, Wilson-Zbinden, Caroline, Kissling, Vera M., Diether, Maren, Arm, Alexandra, Yoo, Haneul, Piazza, Ilaria, Saad, Shady, Picotti, Paola, Drummond, D. Allan, Sauer, Uwe, Dechant, Reinhard, Peter, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7611853/
https://www.ncbi.nlm.nih.gov/pubmed/34616026
http://dx.doi.org/10.1038/s41556-021-00760-4

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