Tumor-induced reshuffling of lipid composition on the ER membrane sustains macrophage survival and pro-tumorigenic activity

Tumor-associated macrophages (TAMs) display pro-tumorigenic phenotypes for supporting tumor progression in response to microenvironmental cues imposed by tumor and stromal cells. However, the underlying mechanisms by which tumor cells instruct TAM behavior remain elusive. Here we uncover that tumor...

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Detalles Bibliográficos
Autores principales: Di Conza, Giusy, Tsai, Chin-Hsien, Gallart-Ayala, Hector, Yu, Yi-Ru, Franco, Fabien, Zaffalon, Lea, Xie, Xin, Li, Xiaoyun, Xiao, Zhengtao, Raines, Lydia N., Falquet, Maryline, Jalil, Antoine, Locasale, Jason W., Percipalle, Piergiorgio, Masson, David, Huang, Stanley Ching-Cheng, Martinon, Fabio, Ivanisevic, Julijana, Ho, Ping-Chih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7611917/
https://www.ncbi.nlm.nih.gov/pubmed/34686867
http://dx.doi.org/10.1038/s41590-021-01047-4

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