Myeloid Metabolism as a New Target for Rejuvenation?—Comments on Restoring Metabolism of Myeloid Cells Reverses Cognitive Decline in Ageing. Nature. 2021 Feb;590(7844):122-128

Research led by Katrin Andreasson suggests that fixing age-induced metabolic defects in myeloid cells would suffice to reverse cognitive impairment and to restore synaptic plasticity to the level of young subjects, at least in mice. This opens up the possibility to develop rejuvenating strategies by...

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Detalles Bibliográficos
Autores principales: Knobloch, Marlen, Paolicelli, Rosa C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7611963/
https://www.ncbi.nlm.nih.gov/pubmed/34754515
http://dx.doi.org/10.20900/immunometab20210034
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author Knobloch, Marlen
Paolicelli, Rosa C.
author_facet Knobloch, Marlen
Paolicelli, Rosa C.
author_sort Knobloch, Marlen
collection PubMed
description Research led by Katrin Andreasson suggests that fixing age-induced metabolic defects in myeloid cells would suffice to reverse cognitive impairment and to restore synaptic plasticity to the level of young subjects, at least in mice. This opens up the possibility to develop rejuvenating strategies by targeting immune dysfunction.
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spelling pubmed-76119632021-11-08 Myeloid Metabolism as a New Target for Rejuvenation?—Comments on Restoring Metabolism of Myeloid Cells Reverses Cognitive Decline in Ageing. Nature. 2021 Feb;590(7844):122-128 Knobloch, Marlen Paolicelli, Rosa C. Immunometabolism Article Research led by Katrin Andreasson suggests that fixing age-induced metabolic defects in myeloid cells would suffice to reverse cognitive impairment and to restore synaptic plasticity to the level of young subjects, at least in mice. This opens up the possibility to develop rejuvenating strategies by targeting immune dysfunction. 2021-10-31 /pmc/articles/PMC7611963/ /pubmed/34754515 http://dx.doi.org/10.20900/immunometab20210034 Text en https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms and conditions of Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Knobloch, Marlen
Paolicelli, Rosa C.
Myeloid Metabolism as a New Target for Rejuvenation?—Comments on Restoring Metabolism of Myeloid Cells Reverses Cognitive Decline in Ageing. Nature. 2021 Feb;590(7844):122-128
title Myeloid Metabolism as a New Target for Rejuvenation?—Comments on Restoring Metabolism of Myeloid Cells Reverses Cognitive Decline in Ageing. Nature. 2021 Feb;590(7844):122-128
title_full Myeloid Metabolism as a New Target for Rejuvenation?—Comments on Restoring Metabolism of Myeloid Cells Reverses Cognitive Decline in Ageing. Nature. 2021 Feb;590(7844):122-128
title_fullStr Myeloid Metabolism as a New Target for Rejuvenation?—Comments on Restoring Metabolism of Myeloid Cells Reverses Cognitive Decline in Ageing. Nature. 2021 Feb;590(7844):122-128
title_full_unstemmed Myeloid Metabolism as a New Target for Rejuvenation?—Comments on Restoring Metabolism of Myeloid Cells Reverses Cognitive Decline in Ageing. Nature. 2021 Feb;590(7844):122-128
title_short Myeloid Metabolism as a New Target for Rejuvenation?—Comments on Restoring Metabolism of Myeloid Cells Reverses Cognitive Decline in Ageing. Nature. 2021 Feb;590(7844):122-128
title_sort myeloid metabolism as a new target for rejuvenation?—comments on restoring metabolism of myeloid cells reverses cognitive decline in ageing. nature. 2021 feb;590(7844):122-128
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7611963/
https://www.ncbi.nlm.nih.gov/pubmed/34754515
http://dx.doi.org/10.20900/immunometab20210034
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