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Protocol for a preclinical systematic review and meta-analysis of pharmacological targeting of peroxisome proliferator-activated receptors in experimental renal injury

INTRODUCTION: Impaired lipid metabolism in the renal tubule plays a prominent role in the progression of renal fibrosis following acute kidney injury (AKI) and in chronic kidney disease (CKD). Peroxisome proliferator-activated receptors (PPARs) are promising druggable targets to mitigate renal fibro...

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Detalles Bibliográficos
Autores principales:	Martin, William P, Chuah, Yeong H D, Conroy, Emer, Reynolds, Alison L, Judge, Conor, López-Hernández, Francisco J, le Roux, Carel W, Docherty, Neil G
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2021
Materias:	Protocol
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7612047/ https://www.ncbi.nlm.nih.gov/pubmed/34849404 http://dx.doi.org/10.1136/bmjos-2021-100240

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