Proteogenomics of non-small cell lung cancer reveals molecular subtypes associated with specific therapeutic targets and immune evasion mechanisms

Despite major advancements in lung cancer treatment, long-term survival is still rare, and a deeper understanding of molecular phenotypes would allow the identification of specific cancer dependencies and immune evasion mechanisms. Here we performed in-depth mass spectrometry (MS)-based proteogenomi...

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Detalles Bibliográficos
Autores principales: Lehtiö, Janne, Arslan, Taner, Siavelis, Ioannis, Pan, Yanbo, Socciarelli, Fabio, Berkovska, Olena, Umer, Husen M., Mermelekas, Georgios, Pirmoradian, Mohammad, Jönsson, Mats, Brunnström, Hans, Brustugun, Odd Terje, Purohit, Krishna Pinganksha, Cunningham, Richard, Asl, Hassan Foroughi, Isaksson, Sofi, Arbajian, Elsa, Aine, Mattias, Karlsson, Anna, Kotevska, Marija, Hansen, Carsten Gram, Haakensen, Vilde Drageset, Helland, Åslaug, Tamborero, David, Johansson, Henrik J., Branca, Rui M., Planck, Maria, Staaf, Johan, Orre, Lukas M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7612062/
https://www.ncbi.nlm.nih.gov/pubmed/34870237
http://dx.doi.org/10.1038/s43018-021-00259-9

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