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Functional Impact of Genomic Complexity on the Transcriptome of Multiple Myeloma
PURPOSE: Multiple myeloma is a biologically heterogenous plasma-cell disorder. In this study, we aimed at dissecting the functional impact on transcriptome of gene mutations, copy-number abnormalities (CNA), and chromosomal rearrangements (CR). Moreover, we applied a geno-transcriptomic approach to...
Autores principales: | Ziccheddu, Bachisio, Da Vià, Matteo C., Lionetti, Marta, Maeda, Akihiro, Morlupi, Silvia, Dugo, Matteo, Todoerti, Katia, Oliva, Stefania, D'Agostino, Mattia, Corradini, Paolo, Landgren, Ola, Iorio, Francesco, Pettine, Loredana, Pompa, Alessandra, Manzoni, Martina, Baldini, Luca, Neri, Antonino, Maura, Francesco, Bolli, Niccolò |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for Cancer Research
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7612071/ https://www.ncbi.nlm.nih.gov/pubmed/34526359 http://dx.doi.org/10.1158/1078-0432.CCR-20-4366 |
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