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Ring Expansion of 1-Indanones to 2-Halo-1-naphthols as an Entry Point to Gilvocarcin Natural Products
[Image: see text] Herein, we describe a two-step ring expansion of 1-indanones to afford 2-chloro/bromo-1-naphthols (32 examples). The developed method shows broad functional group tolerance, benefits from mild reaction conditions, and enables rapid access to the tetracyclic core of gilvocarcin natu...
Autores principales: | Zamarija, Ivica, Marsh, Benjamin J., Magauer, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7612072/ https://www.ncbi.nlm.nih.gov/pubmed/34780199 http://dx.doi.org/10.1021/acs.orglett.1c03530 |
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