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Identification of 371 genetic variants for age at first sex and birth linked to externalising behaviour

Age at first sexual intercourse (AFS) and age at first birth (AFB) have implications for health and evolutionary fitness. In this genome-wide association study (AFS, N=387,338; AFB, N=542,901), we identify 371 SNPs, 11 sex-specific, with a 5-6% polygenic score (PGS) prediction. Heritability of AFB s...

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Detalles Bibliográficos
Autores principales: Mills, Melinda C., Tropf, Felix C., Brazel, David M., van Zuydam, Natalie, Vaez, Ahmad, Pers, Tune H., Snieder, Harold, Perry, John R.B., Ong, Ken K., den Hoed, Marcel, Barban, Nicola, Day, Felix R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7612120/
https://www.ncbi.nlm.nih.gov/pubmed/34211149
http://dx.doi.org/10.1038/s41562-021-01135-3