Gene expression changes contribute to stemness and therapy resistance of relapsed acute myeloid leukemia: roles of SOCS2, CALCRL, MTSS1, and KDM6A

Relapse is associated with therapy resistance and is a major cause of death in acute myeloid leukemia (AML). It is thought to result from the accretion of therapy-refractory leukemic stem cells. Genetic and transcriptional changes that are recurrently gained at relapse are likely to contribute to th...

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Detalles Bibliográficos
Autores principales: Grandits, Alexander M., Wieser, Rotraud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7612147/
https://www.ncbi.nlm.nih.gov/pubmed/34029637
http://dx.doi.org/10.1016/j.exphem.2021.05.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7612147/
https://www.ncbi.nlm.nih.gov/pubmed/34029637
http://dx.doi.org/10.1016/j.exphem.2021.05.004

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