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A stochastically curtailed two-arm randomised phase II trial design for binary outcomes
Randomised controlled trials are considered the gold standard in trial design. However, phase II oncology trials with a binary outcome are often single-arm. Although a number of reasons exist for choosing a single-arm trial, the primary reason is that single-arm designs require fewer participants th...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7612167/ https://www.ncbi.nlm.nih.gov/pubmed/32860470 http://dx.doi.org/10.1002/pst.2067 |