Cargando…
Accurate prediction of protein structures and interactions using a 3-track neural network
DeepMind presented remarkably accurate predictions at the recent CASP14 protein structure prediction assessment conference. We explored network architectures incorporating related ideas and obtained the best performance with a 3-track network in which information at the 1D sequence level, the 2D dis...
Autores principales: | Baek, Minkyung, DiMaio, Frank, Anishchenko, Ivan, Dauparas, Justas, Ovchinnikov, Sergey, Lee, Gyu Rie, Wang, Jue, Cong, Qian, Kinch, Lisa N., Schaeffer, R. Dustin, Millán, Claudia, Park, Hahnbeom, Adams, Carson, Glassman, Caleb R., DeGiovanni, Andy, Pereira, Jose H., Rodrigues, Andria V., van Dijk, Alberdina A., Ebrecht, Ana C., Opperman, Diederik J., Sagmeister, Theo, Buhlheller, Christoph, Pavkov-Keller, Tea, Rathinaswamy, Manoj K, Dalwadi, Udit, Yip, Calvin K, Burke, John E, Garcia, K. Christopher, Grishin, Nick V., Adams, Paul D., Read, Randy J., Baker, David |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7612213/ https://www.ncbi.nlm.nih.gov/pubmed/34282049 http://dx.doi.org/10.1126/science.abj8754 |
Ejemplares similares
-
Improved protein structure refinement guided by deep learning based accuracy estimation
por: Hiranuma, Naozumi, et al.
Publicado: (2021) -
Protein tertiary structure prediction and refinement using deep learning and Rosetta in CASP14
por: Anishchenko, Ivan, et al.
Publicado: (2021) -
Structure of the phosphoinositide 3-kinase (PI3K) p110γ-p101 complex reveals molecular mechanism of GPCR activation
por: Rathinaswamy, Manoj K., et al.
Publicado: (2021) -
Protein oligomer modeling guided by predicted interchain contacts in CASP14
por: Baek, Minkyung, et al.
Publicado: (2021) -
Large-scale determination of previously unsolved protein structures using evolutionary information
por: Ovchinnikov, Sergey, et al.
Publicado: (2015)