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Engineering Crystal Packing in RNA-Protein Complexes II: A Historical Perspective from the Structural Studies of the Spliceosome

Cryo-electron microscopy has greatly advanced our understanding of how the spliceosome cycles through different conformational states to conduct the chemical reactions that remove introns from pre-mRNA transcripts. The Cryo-EM structures were built upon decades of crystallographic studies of various...

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Detalles Bibliográficos
Autores principales:	Leung, Adelaine Kwun-Wai, Kondo, Yasushi, Krummel, Daniel A. Pomeranz, Li, Jade, Price, Stephen R., van Roon, Anne-Marie M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7612351/ https://www.ncbi.nlm.nih.gov/pubmed/35154816 http://dx.doi.org/10.3390/cryst11080948

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