Functional and Biochemical Consequences of Disease Variants in Neurotransmitter Transporters: A Special Emphasis on Folding and Trafficking Deficits

Neurotransmitters, such as γ-aminobutyric acid, glutamate, acetyl choline, glycine and the monoamines, facilitate the crosstalk within the central nervous system. The designated neurotransmitter transporters (NTTs) both release and take up neurotransmitters to and from the synaptic cleft. NTT dysfun...

Descripción completa

Detalles Bibliográficos
Autores principales: Bhat, Shreyas, El-Kasaby, Ali, Freissmuth, Michael, Sucic, Sonja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7612411/
https://www.ncbi.nlm.nih.gov/pubmed/33310157
http://dx.doi.org/10.1016/j.pharmthera.2020.107785

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7612411/
https://www.ncbi.nlm.nih.gov/pubmed/33310157
http://dx.doi.org/10.1016/j.pharmthera.2020.107785

Ejemplares similares