Shorter treatment for non-severe tuberculosis in African and Indian children

BACKGROUND: Two-thirds of children with tuberculosis have non-severe disease. METHOD: SHINE was an open-label treatment-shortening non-inferiority trial in children with non-severe, symptomatic, presumed drug-susceptible, smear-negative tuberculosis, in Uganda, Zambia, South Africa and India. Childr...

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Autores principales: Turkova, Anna, Wills, Genevieve H, Wobudeya, Eric, Chabala, Chishala, Palmer, Megan, Kinikar, Aarti, Hissar, Syed, Choo, Louise, Musoke, Philippa, Mulenga, Veronica, Mave, Vidya, Joseph, Bency, LeBeau, Kirsten, Thomason, Margaret J, Mboizi, Robert B, Kapasa, Monica, van der Zalm, Marieke, Raichur, Priyanka, Bhavani, Perumal Kannabiran, McIlleron, Helen, Demers, Anne-Marie, Aarnouste, Rob, Love-Koh, James, Seddon, James A, Welch, Steven B, Graham, Stephen M, Hesseling, Anneke, Gibb, Diana M, Crook, Angela M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7612496/
https://www.ncbi.nlm.nih.gov/pubmed/35263517
http://dx.doi.org/10.1056/NEJMoa2104535

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