Comment on ‘Numerical assessment and comparison of pulse wave velocity methods aiming at measuring aortic stiffness’

A recent numerical study investigated the potential utility of peripheral PWV measurements for assessing aortic stiffness by simulating pulse wave propagation through the arterial tree. In this Comment we provide additional analysis of the simulations in which arterial compliances were changed. The...

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Autores principales: Charlton, Peter H., Willemet, Marie, Chowienczyk, Phil, Alastruey, Jordi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7612522/
https://www.ncbi.nlm.nih.gov/pubmed/29869992
http://dx.doi.org/10.1088/1361-6579/aaca80
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author Charlton, Peter H.
Willemet, Marie
Chowienczyk, Phil
Alastruey, Jordi
author_facet Charlton, Peter H.
Willemet, Marie
Chowienczyk, Phil
Alastruey, Jordi
author_sort Charlton, Peter H.
collection PubMed
description A recent numerical study investigated the potential utility of peripheral PWV measurements for assessing aortic stiffness by simulating pulse wave propagation through the arterial tree. In this Comment we provide additional analysis of the simulations in which arterial compliances were changed. The analysis indicates that relationships between aortic and peripheral pulse transit times (PTTs) may not be constant when compliances change. Consequently, peripheral PWV measurements may have greatest utility in particular clinical settings in which either: an assumption can be made about possible changes in compliance, allowing aortic PTT to be estimated from peripheral PTT; or, one wishes to assess changes in peripheral PWV over time.
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spelling pubmed-76125222022-03-21 Comment on ‘Numerical assessment and comparison of pulse wave velocity methods aiming at measuring aortic stiffness’ Charlton, Peter H. Willemet, Marie Chowienczyk, Phil Alastruey, Jordi Physiol Meas Article A recent numerical study investigated the potential utility of peripheral PWV measurements for assessing aortic stiffness by simulating pulse wave propagation through the arterial tree. In this Comment we provide additional analysis of the simulations in which arterial compliances were changed. The analysis indicates that relationships between aortic and peripheral pulse transit times (PTTs) may not be constant when compliances change. Consequently, peripheral PWV measurements may have greatest utility in particular clinical settings in which either: an assumption can be made about possible changes in compliance, allowing aortic PTT to be estimated from peripheral PTT; or, one wishes to assess changes in peripheral PWV over time. 2018-07-06 2018-07-06 /pmc/articles/PMC7612522/ /pubmed/29869992 http://dx.doi.org/10.1088/1361-6579/aaca80 Text en https://creativecommons.org/licenses/by-nc-nd/3.0/As the Version of Record of this article is going to be / has been published on a subscription basis, this Accepted Manuscript is available for reuse under a CC BY-NC-ND 3.0 licence after the 12 month embargo period. After the embargo period, everyone is permitted to use copy and redistribute this article for non-commercial purposes only, provided that they adhere to all the terms of the licence (https://creativecommons.org/licenses/by-nc-nd/3.0/ Although reasonable endeavours have been taken to obtain all necessary permissions from third parties to include their copyrighted content within this article, their full citation and copyright line may not be present in this Accepted Manuscript version. Before using any content from this article, please refer to the Version of Record on IOPscience once published for full citation and copyright details, as permissions will likely be required. All third party content is fully copyright protected, unless specifically stated otherwise in the figure caption in the Version of Record.
spellingShingle Article
Charlton, Peter H.
Willemet, Marie
Chowienczyk, Phil
Alastruey, Jordi
Comment on ‘Numerical assessment and comparison of pulse wave velocity methods aiming at measuring aortic stiffness’
title Comment on ‘Numerical assessment and comparison of pulse wave velocity methods aiming at measuring aortic stiffness’
title_full Comment on ‘Numerical assessment and comparison of pulse wave velocity methods aiming at measuring aortic stiffness’
title_fullStr Comment on ‘Numerical assessment and comparison of pulse wave velocity methods aiming at measuring aortic stiffness’
title_full_unstemmed Comment on ‘Numerical assessment and comparison of pulse wave velocity methods aiming at measuring aortic stiffness’
title_short Comment on ‘Numerical assessment and comparison of pulse wave velocity methods aiming at measuring aortic stiffness’
title_sort comment on ‘numerical assessment and comparison of pulse wave velocity methods aiming at measuring aortic stiffness’
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7612522/
https://www.ncbi.nlm.nih.gov/pubmed/29869992
http://dx.doi.org/10.1088/1361-6579/aaca80
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