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High-throughput functional characterization of protein phosphorylation sites in yeast

Phosphorylation is a critical post-translational modification involved in the regulation of almost all cellular processes. However, less than 5% of thousands of recently discovered phosphosites have been functionally annotated. Here, we devised a chemical genetic approach to study the functional rel...

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Detalles Bibliográficos
Autores principales: Viéitez, Cristina, Busby, Bede P., Ochoa, David, Mateus, André, Memon, Danish, Galardini, Marco, Yildiz, Umut, Trovato, Matteo, Jawed, Areeb, Geiger, Alexander G., Oborská-Oplová, Michaela, Potel, Clement M., Vonesch, Sibylle C., Tu, Chelsea Szu, Shahraz, Mohammed, Stein, Frank, Steinmetz, Lars M., Panse, Vikram G., Noh, Kyung-Min, Savitski, Mikhail M., Typas, Athanasios, Beltrao, Pedro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7612524/
https://www.ncbi.nlm.nih.gov/pubmed/34663920
http://dx.doi.org/10.1038/s41587-021-01051-x