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Tumor-Derived Lactic Acid Modulates Activation and Metabolic Status of Draining Lymph Node Stroma

Communication between tumors and the stroma of tumor-draining lymph nodes (TDLN) exists before metastasis arises, altering the structure and function of the TDLN niche. Transcriptional profiling of fibroblastic reticular cells (FRC), the dominant stromal population of lymph nodes, has revealed that...

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Detalles Bibliográficos
Autores principales:	Riedel, Angela, Helal, Moutaz, Pedro, Luisa, Swietlik, Jonathan J., Shorthouse, David, Schmitz, Werner, Haas, Lisa, Young, Timothy, da Costa, Ana S.H., Davidson, Sarah, Bhandare, Pranjali, Wolf, Elmar, Hall, Benjamin A., Frezza, Christian, Oskarsson, Thordur, Shields, Jacqueline D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for Cancer Research 2022
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7612582/ https://www.ncbi.nlm.nih.gov/pubmed/35362044 http://dx.doi.org/10.1158/2326-6066.CIR-21-0778

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