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The Candida albicans toxin candidalysin mediates distinct epithelial inflammatory responses through p38 and EGFR-ERK pathways

The fungal pathogen Candida albicans secretes the peptide toxin candidalysin, which damages epithelial cells and drives an innate inflammatory response mediated by the epidermal growth factor receptor (EGFR) and mitogen-activated protein kinase (MAPK) pathways and the transcription factor c-Fos. In...

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Detalles Bibliográficos
Autores principales:	Nikou, Spyridoula-Angeliki, Zhou, Chunsheng, Griffiths, James S., Kotowicz, Natalia K., Coleman, Bianca M., Green, Mary J., Moyes, David L., Gaffen, Sarah L., Naglik, Julian R., Parker, Peter J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7612652/ https://www.ncbi.nlm.nih.gov/pubmed/35380879 http://dx.doi.org/10.1126/scisignal.abj6915

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