Cargando…

Wireless MRI‐Powered Reversible Orientation‐Locking Capsule Robot

Magnetic resonance imaging (MRI) scanners do not provide only high‐resolution medical imaging but also magnetic robot actuation and tracking. However, the rotational motion capabilities of MRI‐powered wireless magnetic capsule‐type robots have been limited due to the very high axial magnetic field i...

Descripción completa

Detalles Bibliográficos
Autores principales: Erin, Onder, Boyvat, Mustafa, Lazovic, Jelena, Tiryaki, Mehmet Efe, Sitti, Metin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7612672/
https://www.ncbi.nlm.nih.gov/pubmed/35478933
http://dx.doi.org/10.1002/advs.202100463
_version_ 1783605397101215744
author Erin, Onder
Boyvat, Mustafa
Lazovic, Jelena
Tiryaki, Mehmet Efe
Sitti, Metin
author_facet Erin, Onder
Boyvat, Mustafa
Lazovic, Jelena
Tiryaki, Mehmet Efe
Sitti, Metin
author_sort Erin, Onder
collection PubMed
description Magnetic resonance imaging (MRI) scanners do not provide only high‐resolution medical imaging but also magnetic robot actuation and tracking. However, the rotational motion capabilities of MRI‐powered wireless magnetic capsule‐type robots have been limited due to the very high axial magnetic field inside the MRI scanner. Medical functionalities of such robots also remain a challenge due to the miniature robot designs. Therefore, a wireless capsule‐type reversible orientation‐locking robot (REVOLBOT) is proposed that has decoupled translational motion and planar orientation change capability by locking and unlocking the rotation of a spherical ferrous bead inside the robot on demand. Such an on‐demand locking/unlocking mechanism is achieved by a phase‐changing wax material in which the ferrous bead is embedded inside. Controlled and on‐demand hyperthermia and drug delivery using wireless power transfer‐based Joule heating induced by external alternating magnetic fields are the additional features of this robot. The experimental feasibility of the REVOLBOT prototype with steerable navigation, medical function, and MRI tracking capabilities with an 1.33 Hz scan rate is demonstrated inside a preclinical 7T small‐animal MRI scanner. The proposed robot has the potential for future clinical use in teleoperated minimally invasive treatment procedures with hyperthermia and drug delivery capabilities while being wirelessly powered and monitored inside MRI scanners.
format Online
Article
Text
id pubmed-7612672
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher John Wiley and Sons Inc.
record_format MEDLINE/PubMed
spelling pubmed-76126722022-04-26 Wireless MRI‐Powered Reversible Orientation‐Locking Capsule Robot Erin, Onder Boyvat, Mustafa Lazovic, Jelena Tiryaki, Mehmet Efe Sitti, Metin Adv Sci (Weinh) Research Articles Magnetic resonance imaging (MRI) scanners do not provide only high‐resolution medical imaging but also magnetic robot actuation and tracking. However, the rotational motion capabilities of MRI‐powered wireless magnetic capsule‐type robots have been limited due to the very high axial magnetic field inside the MRI scanner. Medical functionalities of such robots also remain a challenge due to the miniature robot designs. Therefore, a wireless capsule‐type reversible orientation‐locking robot (REVOLBOT) is proposed that has decoupled translational motion and planar orientation change capability by locking and unlocking the rotation of a spherical ferrous bead inside the robot on demand. Such an on‐demand locking/unlocking mechanism is achieved by a phase‐changing wax material in which the ferrous bead is embedded inside. Controlled and on‐demand hyperthermia and drug delivery using wireless power transfer‐based Joule heating induced by external alternating magnetic fields are the additional features of this robot. The experimental feasibility of the REVOLBOT prototype with steerable navigation, medical function, and MRI tracking capabilities with an 1.33 Hz scan rate is demonstrated inside a preclinical 7T small‐animal MRI scanner. The proposed robot has the potential for future clinical use in teleoperated minimally invasive treatment procedures with hyperthermia and drug delivery capabilities while being wirelessly powered and monitored inside MRI scanners. John Wiley and Sons Inc. 2021-05-03 /pmc/articles/PMC7612672/ /pubmed/35478933 http://dx.doi.org/10.1002/advs.202100463 Text en © 2021 The Authors. Advanced Science published by Wiley‐VCH GmbH https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Articles
Erin, Onder
Boyvat, Mustafa
Lazovic, Jelena
Tiryaki, Mehmet Efe
Sitti, Metin
Wireless MRI‐Powered Reversible Orientation‐Locking Capsule Robot
title Wireless MRI‐Powered Reversible Orientation‐Locking Capsule Robot
title_full Wireless MRI‐Powered Reversible Orientation‐Locking Capsule Robot
title_fullStr Wireless MRI‐Powered Reversible Orientation‐Locking Capsule Robot
title_full_unstemmed Wireless MRI‐Powered Reversible Orientation‐Locking Capsule Robot
title_short Wireless MRI‐Powered Reversible Orientation‐Locking Capsule Robot
title_sort wireless mri‐powered reversible orientation‐locking capsule robot
topic Research Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7612672/
https://www.ncbi.nlm.nih.gov/pubmed/35478933
http://dx.doi.org/10.1002/advs.202100463
work_keys_str_mv AT erinonder wirelessmripoweredreversibleorientationlockingcapsulerobot
AT boyvatmustafa wirelessmripoweredreversibleorientationlockingcapsulerobot
AT lazovicjelena wirelessmripoweredreversibleorientationlockingcapsulerobot
AT tiryakimehmetefe wirelessmripoweredreversibleorientationlockingcapsulerobot
AT sittimetin wirelessmripoweredreversibleorientationlockingcapsulerobot