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Tumor ENPP1 (CD203a)/Haptoglobin Axis Exploits Myeloid-Derived Suppressor Cells to Promote Post-Radiotherapy Local Recurrence in Breast Cancer
ABSTRACT: Locoregional failure (LRF) in patients with breast cancer post-surgery and post-irradiation is linked to a dismal prognosis. In a refined new model, we identified ectonucleotide pyrophosphatase/phosphodiesterase 1/CD203a (ENPP1) to be closely associated with LRF. ENPP1(hi) circulating tumo...
Autores principales: | Ruiz-Fernández de Córdoba, Borja, Moreno, Haritz, Valencia, Karmele, Perurena, Naiara, Ruedas, Pablo, Walle, Thomas, Pezonaga-Torres, Alberto, Hinojosa, Juan, Guruceaga, Elisabet, Pineda-Lucena, Antonio, Abengózar-Muela, Marta, Cochonneau, Denis, Zandueta, Carolina, Martínez-Canarias, Susana, Teijeira, Álvaro, Ajona, Daniel, Ortiz-Espinosa, Sergio, Morales, Xabier, Ortiz de Solórzano, Carlos, Santisteban, Marta, Ramos-García, Luis I., Guembe, Laura, Strnad, Vratislav, Heymann, Dominique, Hervás-Stubbs, Sandra, Pío, Rubén, Rodríguez-Ruiz, María E., de Andrea, Carlos E., Vicent, Silvestre, Melero, Ignacio, Lecanda, Fernando, Martínez-Monge, Rafael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for Cancer Research
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7612709/ https://www.ncbi.nlm.nih.gov/pubmed/35191482 http://dx.doi.org/10.1158/2159-8290.CD-21-0932 |
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