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Methaemoglobinaemia and the radical curative efficacy of 8-aminoquinoline antimalarials
Methaemoglobin results from the oxidation of ferrous to ferric iron in the centre of the haem moeity of haemoglobin. The production of dose-dependent methaemoglobinaemia by 8-aminoquinoline antimalarial drugs appears to be associated with, but is not directly linked to, therapeutic efficacy against...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7612727/ https://www.ncbi.nlm.nih.gov/pubmed/34997616 http://dx.doi.org/10.1111/bcp.15219 |