Apelin-driven endothelial cell migration sustains intestinal progenitor cells and tumor growth

Stem and progenitor cells residing in the intestinal crypts drive the majority of colorectal cancers (CRCs), yet vascular contribution to this niche remains largely unexplored. VEGFA is a key driver of physiological and tumor angiogenesis. Accordingly, current anti-angiogenic cancer therapies target...

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Detalles Bibliográficos
Autores principales: Bernier-Latmani, Jeremiah, Cisarovsky, Christophe, Mahfoud, Samantha, Ragusa, Simone, Dupanloup, Isabelle, Barras, David, Renevey, François, Nassiri, Sina, Anderle, Pascale, Squadrito, Mario Leonardo, Siegert, Stefanie, Davanture, Suzel, González-Loyola, Alejandra, Fournier, Nadine, Luther, Sanjiv A., Benedito, Rui, Valet, Philippe, Zhou, Bin, De Palma, Michele, Delorenzi, Mauro, Sempoux, Christine, Petrova, Tatiana V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7612746/
https://www.ncbi.nlm.nih.gov/pubmed/35602406
http://dx.doi.org/10.1038/s44161-022-00061-5

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